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目的分析高龄(≥80岁)女性冠心病(CHD)患者冠脉造影(CAG)特点及冠脉介入治疗的临床疗效。方法比较162例高龄女性冠心病患者(A组)与271例高龄男性CHD患者(B组)临床和冠脉造影的特点及介入治疗的疗效和主要不良心脑血管事件(MACCE)发生率。结果与B组比较,A组患者冠脉血管细小、病变复杂且严重。远期随访结果:A组血运重建率明显高于B组[15.1%(21/139)vs.6.5%(15/230)](P<0.05);A组MACCE发生率略高于B组[12.2%(17/139)vs.8.3%(19/230)](P>0.05)。结论与高龄男性冠心病患者相比,高龄女性CHD患者的冠脉细小、病变复杂,行介入治疗同样安全有效,血运重建率高,但MACCE发生率高。
Objective To analyze the characteristics of coronary angiography (CAG) in elderly patients (≥80 years) with coronary heart disease (CHD) and the clinical effect of coronary intervention. Methods The clinical and coronary angiographic features of 162 elderly women with coronary heart disease (A group) and 271 elderly men with CHD (B group) were compared. The efficacy of interventional therapy and the incidence of major adverse cardiovascular and cerebrovascular events (MACCE) were compared. Results Compared with group B, the coronary vessels in group A were small and complicated and severe. Long-term follow-up results: The rate of revascularization in group A was significantly higher than that in group B [15.1% (21/139 vs vs 2.5% (15/230)] (P <0.05) [12.2% (17/139) vs.8.3% (19/230)] (P> 0.05). Conclusion Compared with elderly men, CHD patients have small coronary arteries and complicated lesions. The interventional treatment is equally safe and effective. The rate of revascularization is high, but the incidence of MACCE is high.