This paper calculated load-carrying of isogrid and orthogrid of carbon-epoxy composite trellis wound structure (C/E CTWS) using non-linear finite element method. Based on the analysis, test cases were designed and tests of axial compression were carried. Analysis result and test result fit well. In order to be used in the project, this kind of structure cut-out repairing was calculated. The method presented in this paper has been proved and can be used to solve complicated engineering problems. According to calculations and experimental results combined with application, a principle of choosing wound structure is obtained and principle could be applied to engineering.