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感染是恶性血液病患者化疗后最常见并发症之一,也是导致患者死亡的主要原因[1]。恶性血液病患者由于其疾病本身特点及多种化疗药物的应用,大多存在不同程度免疫功能缺陷及造血功能的异常。多数患者化疗后进入粒缺期,由于粒缺期长,正常黏膜屏障被破坏,免疫抑制剂、糖皮质激素及广谱抗菌药的长期应用等因素,病原菌侵入血液引发败血症的机会增加。我们对我院2011年12月—2013年5月70例恶性血液病患者化疗后致败血症的临床特点进
Infection is one of the most common complication after chemotherapy in patients with hematologic malignancies and also the leading cause of death in patients [1]. Due to the characteristics of the disease itself and the application of multiple chemotherapeutic drugs, most patients with hematologic malignancies have abnormalities in immune function and hematopoietic function to varying degrees. Most patients enter the granulomatous stage after chemotherapy, due to the long grain defects, the normal mucosal barrier is destroyed, immunosuppressive agents, glucocorticoids and long-term use of broad-spectrum antimicrobial agents and other factors, pathogenic bacteria into the blood to increase the chances of septicemia. In our hospital from December 2011 -2013 in May 70 cases of malignant hematopathy in patients with chemotherapy-induced sepsis clinical features into