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目的对细胞毒药物的合理应用方法进行分析探讨。方法对原有的细胞毒物配置过程中的问题进行总结,并根据存在的问题采取相应措施,对比改进前后的药物集中配置中的错误率。结果观察组的标签贴错率、配置核对漏错率、细胞毒药物泄漏率为0.02%、0.02%、0.02%,对照组为0.11%、0.09%、0.05%,观察组的标签贴错率、配置核对漏错率、细胞毒药物泄漏率明显低于对照组,差异具有统计学意义(P<0.05)。结论在细胞毒素药物管理过程中进行集中管理可有效降低配置过程中的错误率,提高用药安全性,值得推广借鉴。
Objective To analyze and discuss the rational application of cytotoxic drugs. Methods To summarize the problems in the process of the original cytotoxicity allocation and to take corresponding measures according to the existing problems, and to compare the error rates before and after the improvement in the centralized drug allocation. Results In the observation group, the labeling error rate, the mismatch rate of configuration checking, the leakage rate of cytotoxic drugs were 0.02%, 0.02% and 0.02%, and the control group was 0.11%, 0.09% and 0.05% The misclassification error rate and cytotoxic drug leakage rate were significantly lower than those in the control group, with statistical significance (P <0.05). Conclusion The centralized management in the process of cytotoxic drug administration can effectively reduce the error rate in the configuration process and improve the safety of medication, which is worth to promote.