Flavone Content and Bioactivity of Aqueous-Ethanolic Extracts of Phellinus Fruit Bodies

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The flavone content of aqueous ethanolic extracts of Phellinus fruit bodies obtained from seven different locations was determined.Anti-tumor and antioxidant activities associated with the extracts were investigated in vitro using the Alamar Blue assay and a chemiluminecence-based method,respectively.Extracts of the seven Phellinus samples generated very similar HPLC profiles in qualitative terms although the areas of several peaks varied according to the sample type indicating quantitative differences in the case of some components.All the extracts,especially those of artificially cultivated Phellinus baumii fruit bodies,inhibited L1210 tumor cell proliferation and exhibited superoxide radical scavenging activity although there was no obvious correlation with flavone content. The flavone content of aqueous ethanolic extracts of Phellinus fruit containers obtained from seven different locations was determined.Anti-tumor and antioxidant activities associated with the extracts were investigated in vitro using the Alamar Blue assay and a chemiluminecence-based method,respectively.Extracts of the Seven Phellinus samples produced very similar HPLC profiles in qualitative terms but the several peaks varied according the sample type indicating quantitative slightly differences the the case of some components.All the extracts,especially those of artificially cultivated Phellinus baumii fruit bodies,inhibited L1210 tumor Cell proliferation and exhibited superoxide radical scavenging activity although there was no obvious correlation with flavone content.
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