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生长激素 (GH)作为一种生长发育必需的重要代谢激素 ,在 2 4h内呈脉冲式分泌。主要的脉冲分泌发生在入睡后不久 ,与首次慢波睡眠有关 ,睡眠改变可使脉冲减弱。剥夺睡眠—觉醒周期可抑制GH释放 ,药物刺激延长慢波睡眠可使GH释放增多。GH释放受生长激素释放激素和生长激
Growth hormone (GH) is an important metabolic hormone that is essential for growth and development and is pulsed secreted within 24 hours. The main pulse secretion occurs shortly after falling asleep, related to the first slow wave of sleep, which can be attenuated by changes in sleep. Deprived of sleep - awakening cycle can inhibit the release of GH, drug stimulation to extend slow wave sleep can increase GH release. GH release by growth hormone releasing hormone and growth hormone