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目的 :比较延髓心血管调节中枢受累和其他部位脑肿瘤的心电图改变 ,探讨不同部位脑肿瘤与心电图改变之间的关系及其发生机制。方法 :15 2例脑肿瘤患者分成延髓组、边缘系统组、非边缘系统组 ,分别对其术前心电图进行观察、测量、统计学处理。结果 :48%的患者有心电图异常。延髓组边缘系统组与非边缘系统组比较心电图异常率、校正后的QT间期 (QTc间期 )异常、QTc间期均值、ST段异常、T波异常及窦性心动过速发生均有显著性差异 (P <0 0 5 )。心率延髓组较边缘系统组和非边缘系统组增快 ,有显著性差异 (P <0 0 5 )。结论 :延髓闩部心血管调节中枢受累 ,可以使副交感神经受到抑制 ,交感神经系统兴奋性异常增高 ,产生心率增快、复极障碍为主的心电图改变 ,心电图异常率明显增高。边缘系统损害产生与延髓受累相似的心电图改变 ,非边缘系统组心电图改变与延髓组有显著差异 ,表明脑损害部位与心电图改变之间存在相关性。
OBJECTIVE: To compare the ECG changes involved in medullary regulation of medulla oblongata and brain tumors in other parts of the brain, and to explore the relationship between the different parts of brain tumors and ECG changes and its mechanism. Methods: Fifty-two patients with brain tumor were divided into medulla oblongata group, limbic system group and non-limbic system group. The preoperative electrocardiogram was observed, measured and statistically processed. Results: 48% of patients had ECG abnormalities. Compared with the non-limbic system group, there were significant differences in ECG abnormality, corrected QT interval (QTc interval), QTc interval mean, ST segment abnormality, T wave abnormality and sinus tachycardia Sex differences (P <0 05). Compared with the limbic system group and the non-limbic system group, the systolic pressure group in heart rate increased significantly (P <0.05). Conclusion: The medulla oblongata is involved in the regulation of central cardiovascular system, which can inhibit the parasympathetic nerve, increase the excitability of the sympathetic nervous system, and lead to the change of electrocardiogram with the increase of heart rate and repolarization disorder. The abnormal rate of electrocardiogram is obviously increased. The marginal system damage produced a similar ECG change as the medulla oblongata. The ECG changes in the non-limbic system group were significantly different from those in the medulla oblongata group, indicating that there was a correlation between the brain damage site and the ECG changes.