A new bis-iridoid glucoside, incaside 1 was isolated along with known iridoid, 6-O- veratroylcatalposide from the stem-bark of Mussaenda incana. The structure of the new iridoid was established mainly on the basis of the spectroscopic (including 2D NMR) and chemical studies of its octaacetate 1a. A new bis-iridoid glucoside, incaside 1 was isolated along with known iridoid, 6-O-veratroylcatalpos from the stem-bark of Mussaenda incana. The structure of the new iridoid was established mainly on the basis of the spectroscopic (including 2D NMR) and chemical studies of its octaacetate 1a.