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神经影像学研究经历了从正电子发射扫描(PET)到功能性核磁共振(fMRI)的发展历程。近年来,药效动力学与功能性核磁共振相结合的药理学磁共振(phMRI)在精神疾病的药效动力学、神经认知系统的转运机制、药物的神经生理影响中发挥了巨大的作用,正成为一门新型学科。苯二氮卓类药物是一种应用最广泛的抗焦虑剂,苯二氮卓的神经影像学研究能够为新型抗焦虑剂的开发以及苯二氮卓类药物的应用提供神经学的基础。目前关于苯二氮卓类的神经影像学的文章并不是太多,我们搜集了所有有关于苯二氮卓神经影像学的资料,我们将介绍苯二氮卓类药物结合认知行为学范式或疼痛的神经影像学发现,最后我们将回顾一下这些发现能带来的临床应用。
Neuroimaging has undergone a development from positron emission tomography (PET) to functional magnetic resonance imaging (fMRI). In recent years, pharmacodynamic magnetic resonance (phMRI), a combination of pharmacodynamic and functional nuclear magnetic resonance, has played a significant role in the pharmacodynamics of psychiatric disorders, the transport mechanism of neurocognitive systems, and the neurophysiological effects of drugs , Is becoming a new discipline. Benzodiazepines are the most widely used anxiolytic agents. The benzodiazepine neuroimaging study can provide a neurological foundation for the development of new anti-anxiety agents and benzodiazepines. Currently there are not many articles on benzodiazepine neuroimaging. We have collected all the information about the neurological imaging of benzodiazepine. We will introduce the benzodiazepines combined with cognitive behavioral paradigms or Neuropathological findings of pain, and finally we will review the clinical implications of these findings.