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研究小动脉端端吻合术后血流动力学变化,为进一步的研究提供依据。选用SD大鼠10只,切断左侧颈总动脉行端端吻合。术后6,12,24,48,72和120小时,用彩色多普勒血流仪经皮连续测定实验侧颈总动脉吻合口近端、吻合口、吻合口远端,以及对照侧颈总动脉的收缩期最高血流速度,计算吻合口横切面的狭窄面积百分比。结果显示,术后各个时间段,吻合口收缩期最高血流速度均明显高于吻合口近端、吻合口和对照侧颈总动脉的血流速度(P<0.05);吻合口远端的收缩期血流速度均低于吻合口近端和对照侧颈总动脉的血流速度(P<0.05),血流速度分别降低33.18%和33.33%。术后6小时~120小时均出现不同程度的狭窄,平均减少42.48%。认为,小动脉端端吻合术后6小时~120小时,吻合口血流速度均明显高于吻合口近端和吻合口远端的血流速度;吻合口远端的流速均明显低于吻合口近端的流速;吻合口及其近、远端的血流速度变化不一致。
To study the changes of hemodynamics after arteriolar anastomosis, provide basis for further research. Ten SD rats were selected and the left common carotid artery was transected. At 6, 12, 24, 48, 72 and 120 hours postoperatively, the proximal end of common carotid artery anastomosis, the anastomosis, the distal end of anastomosis, and the control neck were assessed by color Doppler flowmeter Arterial systolic peak blood flow velocity, calculate the anastomotic cross-section of the narrow area percentage. The results showed that at each time after operation, the maximum systolic velocity of anastomosis was significantly higher than that of proximal, anastomotic and control side common carotid arteries (P <0.05) (P <0.05). The blood flow velocity decreased by 33.18% and 33.33% respectively, which was lower than that of proximal and anterolateral anastomosis. Postoperative 6 hours to 120 hours showed varying degrees of stenosis, an average reduction of 42.48%. It is considered that the velocity of anastomosis blood flow is significantly higher than that of the anastomotic proximal and anastomotic distal from 6 hours to 120 hours after arteriolar anastomosis. The flow velocity of distal end of anastomosis is significantly lower than that of anastomotic Proximal velocity; anastomotic and proximal and distal changes in blood flow velocity inconsistent.