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目的探讨同型半胱氨酸在原发性高血压患者中的检测意义。方法选择我院2009年4月至2011年4月原发性高血压患者100例,作为观察组,以上患者诊断均符合原发性高血压诊断标准,以上患者又分为轻度组、中度组和重度组。同时选取我院体检健康者50例,为对照组。清晨抽取空腹静脉血,测定所选患者血浆同型半胱氨酸水平。结果观察组同型半胱氨酸水平与对照组比较,差异有统计学意义(P<0.05)。重度组同型半胱氨酸水平显著高于中度组和轻度组,差异有统计学意义(P<0.05);中度组同型半胱氨酸水平显著高于轻度组,差异有统计学意义(P<0.05)。结论原发性高血压血压越高,血浆同型半胱氨酸水平越高。故测定原发性高血压患者血浆同型半胱氨酸水平有助于原发性高血压的预防和病情监测。
Objective To investigate the significance of homocysteine in patients with essential hypertension. Methods 100 cases of essential hypertension in our hospital from April 2009 to April 2011 were selected as the observation group. The diagnosis of the above patients met the diagnostic criteria of essential hypertension, and the above patients were divided into mild group, moderate Group and severe group. At the same time select 50 cases of physical examination in our hospital, as the control group. Fasting venous blood was drawn early in the day to determine plasma homocysteine levels in selected patients. Results The level of homocysteine in the observation group was significantly higher than that in the control group (P <0.05). The level of homocysteine in severe group was significantly higher than that in moderate group and mild group (P <0.05), and the level of homocysteine in moderate group was significantly higher than that in mild group Significance (P <0.05). Conclusion The higher the blood pressure of essential hypertension, the higher the plasma homocysteine level. Therefore, the determination of plasma homocysteine levels in patients with essential hypertension contribute to the prevention of essential hypertension and disease monitoring.