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目的观察激素联合血浆交换治疗格林巴利综合征疗效。方法对入院的24例格林巴利综合征患者采用分组对照观察,其中观察组应用甲基强地松龙冲击联合血浆交换治疗组12例,对照组应用血浆交换治疗。治疗20d后比较不同治疗方案对格林巴利综合征的疗效。结果两组患者在治疗20d后病情均有好转,观察组疗效与对照组比较疗效差异有统计学意义(P<0.05)。结论甲基强地松龙冲击联合血浆交换对格林巴利综合征疗效均明显优于单纯血浆交换治疗,效果显著,值得临床推广。
Objective To observe the effect of hormone combined with plasma exchange in the treatment of Guillain-Barre syndrome. Methods A total of 24 patients with Guillain-Barre syndrome were enrolled in the study. The observation group was treated with methylprednisolone shock combined with plasma exchange therapy in 12 cases and the control group with plasma exchange therapy. After 20 days of treatment, the curative effect of different treatment regimens on Guillain-Barre syndrome was compared. Results The patients in both groups improved after 20 days of treatment, and there was significant difference in curative effect between the two groups (P <0.05). Conclusions The effect of methylprednisolol impacting plasma exchange on the treatment of Guillain-Barre syndrome is better than that of pure plasma exchange therapy. The results are significant and worthy of clinical promotion.