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呼吸道绿脓杆菌感染的治疗极为困难,治愈率仅为0～17%,死亡率高达53～100%。本文分析75例呼吸道绿脓杆菌感染的病情,这些患者肺部原发病灶以弥漫性支气管炎最多,共46例占61%。其次支气管扩张9例占12%、肺气肿6例占8%,其余为肺炎和慢性支气管炎等。男、女发病率为3:1,平均年龄为57.5岁,46例弥漫性细支气管炎中16例初诊痰培养检出绿脓杆菌,30例则系入院后交叉感染引起,其中21例有菌群交替,开始痰培养为流感杆菌,以后才出现绿脓杆菌。从27例绿脓杆菌患者和15例非绿脓杆菌感染者比较来看,高龄、严重肺功能不全、血气异常者绿脓杆菌感染居多数。
The treatment of respiratory Pseudomonas aeruginosa infection is extremely difficult, the cure rate is only 0 ~ 17%, the mortality rate is as high as 53 ~ 100%. This article analyzes 75 cases of respiratory tract infection with Pseudomonas aeruginosa disease, these patients with primary lung lesions diffuse bronchitis, a total of 46 cases accounted for 61%. Second bronchiectasis in 9 cases accounted for 12%, 6 cases of emphysema accounted for 8%, and the rest for pneumonia and chronic bronchitis. The incidence of males and females was 3: 1, with an average age of 57.5 years. Of the 46 patients with diffuse bronchiolitis, 16 were diagnosed as Pseudomonas aeruginosa by newly diagnosed sputum culture and 30 were caused by cross-infection after admission. Among them, 21 Alternate group, began to sputum culture for influenza bacilli, Pseudomonas aeruginosa later appeared. From 27 cases of Pseudomonas aeruginosa patients and 15 cases of non-Pseudomonas aeruginosa infection comparison, the elderly, severe pulmonary insufficiency, blood gas abnormalities were the majority of Pseudomonas aeruginosa infection.