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目的探讨该院呼吸内科住院患者感染的病原菌分布及耐药趋势,为临床合理应用抗菌药物提供参考依据。方法回顾性分析2013年1月-2015年12月该院呼吸内科住院患者的病原菌分布资料及耐药性监测结果。结果共分离出1953株病原菌,以肺炎克雷伯菌为主,共338株(17.31%);其次为铜绿假单胞菌和鲍曼不动杆菌,分别占11.98%和6.50%。肺炎克雷伯菌对氨苄西林的耐药率较高,铜绿假单胞菌对二代头孢及部分三代头孢均有较高的耐药率,鲍曼不动杆菌对头孢呋辛等二代头孢亦有较高的耐药率。结论呼吸内科住院患者感染的病原菌耐药性日益严重,临床医师应重视耐药性的监测,合理使用抗菌药物。
Objective To investigate the distribution of pathogens and their drug resistance trends in inpatients with respiratory medicine in this hospital and provide a reference for rational use of antibiotics in clinical practice. Methods A retrospective analysis was conducted on the distribution of pathogenic bacteria in hospitalized patients and their drug resistance monitoring results from January 2013 to December 2015 in this hospital. Results A total of 1953 strains were isolated from Klebsiella pneumoniae, 338 (17.31%) were Klebsiella pneumoniae, followed by Pseudomonas aeruginosa and Acinetobacter baumannii, accounting for 11.98% and 6.50% respectively. Klebsiella pneumoniae higher resistance to ampicillin, Pseudomonas aeruginosa second-generation cephalosporins and some third-generation cephalosporins have a higher resistance rate Acinetobacter cephalothin second-generation cephalosporins There is also a higher resistance rate. Conclusion Respiratory medicine inpatients infected with pathogens are increasingly drug-resistant, clinicians should pay attention to the monitoring of drug resistance, rational use of antimicrobial agents.