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pp125~(FAK)为最近发现的一种非受体类胞浆酪氨酸蛋白激酶,具有其独特的结构功能特征,在整合蛋白介导的细胞外基质分子向胞内传递信号中扮演关键性的角色。本文对pp125~(FAK)的分子结构、功能特征及其在整合蛋白信号传递中的作用进行综述。
pp125 ~ (FAK) is a recently discovered non-receptor type cytosolic tyrosine kinase with its unique structural and functional characteristics, which plays an important role in the signal transduction of integrin-mediated extracellular matrix molecules character of. This review summarizes the molecular structure and functional characteristics of pp125 ~ (FAK) and its role in integrin signaling.