目的:探讨胰腺癌合并糖尿病患者的围手术期处理对策。方法:回顾性分析1990年7月到2007年7月我科收治的16例胰腺癌合并糖尿病病例。术前根据糖尿病的不同情况,给予口服降糖药或胰岛素治疗,术中加强血糖监测,及时调整胰岛素用量,术后及时检测血糖,尿糖水平,防止出现并发症。结果:16例患者均手术治疗,术后并发症6例,包括切口感染1例,胰漏1例,胆汁漏1例,腹腔感染1例,肺感染1例,菌血症1例,无高渗性昏迷及酮症酸中毒出现,无围手术期死亡病例。结论:外科治疗仍是胰腺癌合并糖尿病患者的首选治疗,严格控制血糖水平对于患者安全渡过围手术期是非常重要的。 Objective: To investigate the perioperative management of pancreatic cancer patients with diabetes mellitus. Methods: A retrospective analysis of 16 cases of pancreatic cancer with diabetes treated in our department from July 1990 to July 2007 was conducted. Preoperative according to the different conditions of diabetes, given oral hypoglycemic agents or insulin therapy, intraoperative monitoring of blood glucose, timely adjustment of insulin dosage, timely detection of blood glucose, urine sugar level after surgery to prevent complications. Results: Sixteen patients were treated surgically. There were 6 postoperative complications including 1 incision infection, 1 pancreatic leakage, 1 bile leakage, 1 abdominal infection, 1 lung infection, 1 bacteremia without high Osmotic coma and ketoacidosis appear, no perioperative deaths. Conclusion: Surgical treatment is still the first choice for patients with pancreatic cancer complicated by diabetes. Strict control of blood glucose level is very important for the patients to go through the perioperative period safely.