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近年来对于受体的研究取得很大进展并越来越引起人们的重视。原因有二方面:一是多肽激素包括胰岛素首先和细胞膜上相应的特异性受体结合形成激素—受体复合物,然后激活细胞内一系列反应表现其特异的生物效应。因此,激素活力强度除决定于激素本身的浓度外还决定于受体的数目和它对受体的亲合力。这一重要结论的发现大大激起人们对各种生理和病理情况时受体测定的兴趣。二是亲和层析、放射受体测定等新技术的
In recent years, great progress has been made in the research of receptors and more and more attention has been paid to them. There are two reasons: one is that peptide hormones, including insulin, first combine with the corresponding specific receptors on the cell membrane to form hormone-receptor complexes, and then activate a series of reactions in cells to display their specific biological effects. Therefore, in addition to hormone hormone activity depends on the concentration of hormone itself depends on the number of receptors and its receptor affinity. The discovery of this important conclusion has greatly aroused people’s interest in determining receptors for various physiological and pathological conditions. Second, affinity chromatography, radioactive receptor determination and other new technologies