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目的:比较吲哚菁绿(ICG)、纳米碳混悬注射液在乳腺癌前哨淋巴结(SLN)示踪中的应用效果。方法:选择2013年11月—2016年7月收治乳腺癌行前哨淋巴结活检(SLNB)的患者136例,其中以ICG为示踪剂者60例(ICG组),以纳米碳混悬注射液为示踪剂者76例(纳米碳组)。比较两组的相关指标。结果:两组基本临床资料差异无统计学意义(均P>0.05);ICG组与纳米碳组SLN的检出率(96.67%vs.100%)、灵敏度(89.47%vs.95.83%)、假阴性率(10.53%vs.4.17%)、准确率(93.33%vs.98.68%),组间差异均无统计学意义(均P>0.05);ICG组较纳米碳组SLN检出数目少(3.17枚vs.3.92枚,P=0.000),但检出时间短(25.72 min vs.49.29 min,P=0.000);年龄、体质量指数(BMI)并不影响两种方法的SLN检出率及SLNB准确率(均P>0.05)。结论:ICG与纳米碳混悬注射液示踪乳腺癌SLN具有相似的效能,并且均操作简便,便于推广实施。
Objective: To compare the effect of indocyanine green (ICG) and nanocarbon suspension injection in the SLN tracing of breast cancer. Methods: 136 patients with sentinel lymph node biopsy (SLNB) who underwent breast cancer from November 2013 to July 2016 were selected. Sixty ICG patients (ICG group) Tracer in 76 cases (nano-carbon group). Compare the two groups of related indicators. Results: There was no significant difference in the basic clinical data between the two groups (all P> 0.05). The positive rates of SLN (96.67% vs.100%), sensitivity (89.47% vs.95.83% (10.53% vs 4.17%), the accuracy rate was 93.33% vs.98.68%, there was no significant difference between the two groups (all P> 0.05) (P <0.0002), but the detection time was short (25.72 min vs.49.29 min, P = 0.000). The age and body mass index (BMI) did not affect the SLN detection rate and SLNB Accuracy (all P> 0.05). Conclusion: ICG and nanocarbon suspension injection tracing SLN breast cancer have similar efficacy, and are easy to operate, easy to promote the implementation.