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目的 :研究外侧隔核是否是蝎毒产生中枢镇痛作用的重要部分之一。方法 :用玻璃微电极记录束旁核的单位放电 ;通过不锈钢套管向外侧隔核内微量注射 0 .0 3%蝎毒。结果 :外侧隔核内微量注射0 .0 3%蝎毒可以明显地减弱束旁核内的痛兴奋神经元和痛抑制神经元对伤害性刺激的反应。结论 :外侧隔核是蝎毒产生中枢镇痛作用的重要部位之一。
OBJECTIVE: To investigate whether lateral septal core is an important part of the central analgesic effect of scorpion venom. Methods: Glassy microelectrode was used to record the unit discharge of parafascicular nucleus. Through the stainless steel cannula, 0.3% scorpion venom was injected into the lateral septum. Results: Microinjection of 0.3% scorpion venom into the lateral septum significantly attenuated the pain response of pain-stimulating neurons and pain-suppressing neurons in parafascicular nucleus to nociceptive stimuli. Conclusion: The lateral septal nucleus is one of the important sites for the analgesic effect of scorpion venom.