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目的观察进展性缺血性脑卒中患者血清超敏C反应蛋白(hsCRP)变化规律,探讨超敏C反应蛋白在进展性缺血性脑卒中发病中的作用和临床意义。方法分别于患者入院第1d、第3d、第7d和第14d分别检测缺血性脑卒中患者hsCRP水平,比较进展组与非进展组的差异,分析hsCRP动态水平与缺血性脑卒中患者病情的关系。结果进展组第1d、第3d和第7d血清hsCRP水平高于非进展组,差异有显著统计学意义。结论血清hsCRP水平可作为进展性缺血性脑卒中的预测指标。
Objective To observe the changes of serum hsCRP in patients with progressive ischemic stroke and to explore the role and clinical significance of hsCRP in the pathogenesis of progressive ischemic stroke. Methods The levels of hsCRP in ischemic stroke patients were detected on the 1st day, the 3rd day, the 7th day and the 14th day after admission respectively. The differences between the progressive group and the non-progressive group were analyzed. The dynamic changes of hsCRP level and the severity of ischemic stroke were analyzed relationship. Results The serum hsCRP levels in the progression group at 1d, 3d and 7d were significantly higher than those in the non-progression group, the difference was statistically significant. Conclusion Serum hsCRP level can be used as a predictor of progressive ischemic stroke.