[目的]探讨经自动调节持续气道正压通气(Auto-CPAP)滴定前后中度、重度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)病人多导睡眠图差异分析。[方法]给予经多导睡眠监测(PSG)确诊的187例中度、重度OSAHS病人使用Auto-CPAP治疗2 d,观察治疗前后病人睡眠效率、各期睡眠比例、氧减指数、呼吸暂停/低通气指数(AHI)、最低血氧饱和度(LSaO2)和血氧饱和度<90%的比例变化。[结果]应用Auto-CPAP呼吸机滴定治疗OSAHS病人,除睡眠效率外,各项数据与治疗前比较差异均有统计学意义。[结论]应用Auto-CPAP滴定治疗可以使中度、重度OSAHS病人的睡眠结构、夜间低氧血症在短期内明显改善。 [Objective] To investigate the difference of polysomnography between moderate and severe obstructive sleep apnea-hypopnea syndrome (OSAHS) patients before and after Auto-CPAP titration. [Methods] 187 patients with moderate and severe OSAHS confirmed by polysomnography (PSG) were treated with Auto-CPAP for 2 days. The sleep efficiency, sleep rate, oxygen reduction index, apnea / hypopnoea before and after treatment were observed Ventilation index (AHI), the lowest oxygen saturation (LSaO2) and oxygen saturation <90% of the ratio changes. [Results] The application of Auto-CPAP respirator titration in the treatment of OSAHS patients, except for the efficiency of sleep, the data were statistically significant differences compared with before treatment. [Conclusion] The application of Auto-CPAP titration can make the sleep structure and nocturnal hypoxemia of moderate and severe OSAHS patients significantly improve in short term.