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目的：观察芹灵冲剂的退黄降酶作用，以评价芹灵冲剂的退黄降酶效果。方法：在四氯化碳（ＣＣｌ４）、Ｄ－半乳糖胺（Ｄ－Ｇａｌａ）和α－萘异硫氰酸酯（ＡＮＩＴ）３种化学性肝损伤大鼠模型和在体乙型肝炎（ＤＨＢＶ）鸭，用全自动生化测定仪分别测定动物的肝功能。结果：芹灵冲剂５ｇ·ｋｇ－１和１０ｇ·ｋｇ－１能显著降低ＣＣｌ４和Ｄ－Ｇａｌａ肝损伤大鼠血清谷丙转氨酶（ＡＬＴ）水平。能明显降低ＡＮＩＴ肝损伤大鼠血中胆红素（ＳＢ）含量；对ＤＨＢＶ性肝炎鸭血中ＡＬＴ和ＳＢ水平的升高也有一定降低作用。结论：芹灵冲剂对大鼠化学性肝损伤和鸭乙型肝炎均有显著的退黄降酶作用。
OBJECTIVE: To observe the anti-yellow and enzymatic effects of Qinling Granules in order to evaluate the effect of Qinling Granules on yellowing and descending enzymes. METHODS: Three chemical liver injury models and carbon tetrachloride (CCl4), D-galactosamine (D-Gala) and α-naphthalene isothiocyanate (ANIT) in rats and in vivo hepatitis B (DHBV) ) Ducks were measured for liver function using an automatic biochemical analyzer. RESULTS: The serum concentration of 5g·kg-1 and 10g·kg-1 of QL can significantly reduce the serum ALT levels in rats with liver injury induced by CCl4 and D-Gala. It can significantly reduce the serum bilirubin (SB) content in rats with ANIT liver injury, and it can also reduce the increase of ALT and SB levels in DHBV hepatitis. Conclusion: QLH has a significant effect on chemical liver injury and duck hepatitis B in rats.