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【目的】考察两面针4个部位(根、茎、叶、地上部分)对大鼠胃黏膜损伤的影响,为两面针扩大药用部位提供参考。【方法】观察两面针根、茎、叶、地上部分对盐酸乙醇致大鼠胃黏膜损伤的影响,同时观察不同剂量两面针叶对消炎痛致大鼠胃黏膜损伤的影响。【结果】两面针根、茎、叶、地上部分均可减轻盐酸乙醇所致大鼠胃黏膜损伤;30 g.kg-1.d-1剂量两面针叶可减轻消炎痛所致大鼠胃黏膜损伤。【结论】两面针根、茎、叶及地上部分均具有一定的胃黏膜保护作用。
【Objective】 To investigate the effect of four-sided needle (root, stem, leaf, aerial part) on gastric mucosal lesion in rats and to provide reference for expanding the medicinal part of the two-sided needle. 【Method】 The gastric mucosal injury induced by ethanolic ethanol was observed, and the effects of different doses of two-sided needles on the gastric mucosal injury induced by indomethacin were observed. 【Results】 The gastric mucosal injury induced by ethanolic ethanol could be alleviated by the roots, stems, leaves and aerial parts of the two-sided needle. Both doses of 30 g · kg-1.d-1 coniferous needles could reduce the gastric mucosa of rats induced by indomethacin damage. 【Conclusion】 The root, stem, leaf and aerial parts of the two-sided needle all have certain gastric mucosal protective effects.