急性有机磷农药中毒(acute organophosphorus pesticide poisoning,AOPP)仍然是目前引起人类中毒和死亡的最重要原因之一。据WHO估计,全球每年约有300万AOPP患者,主要集中在发展中国家,其中约25万死亡。而我国每年农药中毒患者超过10万,其中50%以上为AOPP,病死率为10%~15%。AOPP起病急、进展快,主要表现为急性胆碱能危象、中间型综合征、迟发性周围神 Acute organophosphorus pesticide poisoning (AOPP) remains one of the most important causes of human poisoning and death. According to WHO, there are about 3 million AOPP patients in the world each year, mainly in developing countries, of which about 250,000 are dead. In China, there are more than 100,000 pesticide poisoning patients each year, of which more than 50% are AOPP and the case fatality rate is 10% -15%. AOPP acute onset, rapid progress, mainly as acute cholinergic crisis, intermediate syndrome, delayed peripheral god