论文部分内容阅读
目的:分析右旋糖酐氨基酸注射液(DAAI)致不良反应的病例报告,为临床合理用药提供参考。方法:检索国内医药数据库,下载病例报告原文,进行统计分析。结果:共检索到24例不良反应的病例报告,男16例,女8例;2例有药物过敏史,1例有哮喘病史;不良反应以过敏反应为主,过敏性休克占比最高(19例,79.2%),且全部发生在用药后30 min以内。24例中2例老年患者(60岁和84岁)因过敏性休克死亡。结论:医务人员应重视DAAI的不良反应,尤其对过敏性休克这种致命不良反应更要有清醒的认识。
Objective: To analyze the case reports of adverse reactions caused by dextran amino acid injection (DAAI), and to provide a reference for clinical rational drug use. Methods: Retrieve the domestic medical database, download the original case report for statistical analysis. Results: A total of 24 cases of adverse reactions were retrieved, including 16 males and 8 females. Two patients had history of drug allergy and one had asthma history. The main adverse reactions were anaphylactic reaction and the highest proportion of anaphylactic shock (19 Cases, 79.2%), and all occurred within 30 min after treatment. Two of 24 elderly patients (60 and 84 years old) died of anaphylactic shock. Conclusion: Medical staff should pay attention to the adverse reactions of DAAI, especially for the fatal adverse reactions such as anaphylactic shock.