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目前特发性炎性肌病(IIM)病因未明,多认为主要与自身免疫功能失调有关。此文综述了IIM的免疫学发病机制、各亚型组织病理和免疫病理特点,以及可能与此病有关的协同刺激分子的作用。
The current idiopathic inflammatory myopathies (IIM) etiology is unknown, and more that mainly associated with autoimmune dysfunction. This review summarizes the immunological pathogenesis of IIM, the histopathological and immunopathological features of each subtype, and the role of costimulatory molecules that may be involved in the disease.