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目的:探讨A型肉毒毒素(BTX-A)注射结合肌力训练对痉挛型双瘫患儿粗大运动功能的影响。方法:将72例痉挛型双瘫患儿依据其意愿分为观察组39例和对照组33例,均进行综合康复训练,且观察组在此基础上加用BTX-A注射和肌力训练。治疗前和治疗3个月后分别采用改良Ashworth量表(MAS)和粗大运动功能测试量表(GMFM)中站立相(D)和走、跑、攀登相(E)二项进行疗效评估。结果:治疗前后两组MAS评分和GMFM中D项、E项评分比较差异均有统计学意义(P<0.01),且治疗后两组比较差异均有统计学意义(P<0.05)。结论:BTX-A注射结合肌力训练能快速有效地缓解痉挛型双瘫患儿下肢肌肉的痉挛,提高患儿粗大运动功能。
Objective: To investigate the effect of botulinum toxin type A (BTX-A) injection combined with strength training on gross motor function in spastic bipolar children. Methods: Seventy-two children with spastic diplegia were divided into observation group (39 cases) and control group (33 cases) according to their wishes. All children underwent comprehensive rehabilitation training. The observation group received BTX-A injection and strength training. Before treatment and 3 months after treatment, the efficacy of the modified Ashworth scale (MAS) and the gross motor function test (GMFM) standing phase (D) and walking, running, climbing phase (E) were evaluated. Results: Before and after treatment, the scores of D and E in the two groups of MAS score and GMFM were significantly different (P <0.01), and the differences between the two groups after treatment were statistically significant (P <0.05). Conclusion: BTX-A injection combined with strength training can quickly and effectively relieve the spasticity of the lower extremity muscles in children with spastic diplegia and improve the gross motor function in children.