本文遵循疾病过程中的因果转换规律和相对阶段姓，提出动脉粥样硬化（ＡＳ），是一个由原始病因和继发病因所组成的多因性疾病，认为ＡＳ一旦被原始病因启动，则与病变互为因果，推动着疾病的发生、发展和形成，三阶段新老病变互相重叠，表现了疾病阶段的相对性。在发生阶段是原始病因造就了脂质代谢紊乱和动脉管壁损伤两原始病理结果，前者是ＡＳ特异性的物质基础，后者是ＡＳ的管壁发病环境，两者缺一不可。随着病程进展，原始结果又转换为下一阶段的继发病因，二因协同，引发出三种病理现象，即脂质向损伤内膜病理性入侵、沉积；血小板在损伤内膜面上的粘聚、释放和血栓形成；平滑肌细胞的增殖、移行和分泌，三者不仅推动了ＡＳ的发展，同时又是第三阶段中脂滴、脂纹和纤维粥斑等病变产生的直接原因。病变反复发生，结果逐渐导致动脉管壁增厚、管腔狭窄、闭塞或破裂出血……完成了ＡＳ的全过程，并在临床上出现一组相应器官或组织的缺血性或出血坏死性的临床综合征。 This article follows the law of causality in the disease process and the relative stage surname, put forward atherosclerosis (AS), is a multifactorial disease caused by the original cause and secondary cause of disease, that AS once the original cause is activated, and Lesions Mutual cause and effect, promote the occurrence, development and formation of disease, three stages of new and old lesions overlap each other, showing the relative stage of the disease. In the stage of occurrence is the original etiology of lipid metabolism and arterial wall damage caused by the two original pathological results, the former is AS-specific material basis, the latter is the wall of AS disease environment, both indispensable. As the course of the disease progresses, the original result is converted into the secondary cause of the next stage. The two causes three pathological phenomena, namely, the pathological invasion and deposition of the lipid into the injured endometrium, and the platelets are on the injured endocardial surface Cohesion, release and thrombosis; smooth muscle cell proliferation, migration and secretion, three not only promote the development of AS, but also the third phase in the lipid droplets, lipid pattern and fibrosis and other lesions caused by the direct cause. Lesions occur repeatedly, the result gradually lead to thickening of the arterial wall, stenosis, occlusion or rupture of bleeding ... ... completed the entire process of AS, and clinically there is a corresponding organ or tissue ischemic or hemorrhagic necrosis Clinical syndrome.