肿瘤的发生和转移依赖于血管新生 ,这一概念的提出为肿瘤及血管新生相关性疾病的治疗提供了新的方法。基于对肿瘤血管新生机制、血管新生抑制剂的作用机制及特点的研究 ,目前已开发出了多种血管新生抑制剂 ,其中多数已进入了临床实验 The occurrence and metastasis of tumors are dependent on angiogenesis. The concept of this concept provides a new method for the treatment of cancer and angiogenesis-related diseases. Based on the mechanisms of tumor angiogenesis and angiogenesis inhibitors and the characteristics of the study, has developed a variety of angiogenesis inhibitors, most of which have entered clinical trials