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作为围生期(通常指孕期满28周至生后一周)的小儿,包括从不足1千克的早产儿至正常产的巨大婴儿这样一个范围。由于每个婴儿出生前的环境、母亲的健康状况和妊娠分娩的经过不同,其生理适应性均有差异。药物在新生儿体内的代谢与成人有着很大的不同。只有详细了解新生儿的生理特点,才能明确这些医源性疾病的起因,正确应用药物。 很多药物通过肝肾代谢,因新生儿的肝肾功能尚未
As a perinatal period (usually refers to gestational age from 28 weeks to one week after birth) of children, including less than 1 kg of premature babies to normal production of such a huge baby. Because of the prenatal environment of each infant, the health status of the mother differs from that during pregnancy and childbirth, there are differences in physiological adaptability. The metabolism of drugs in newborns is very different from that of adults. Only a detailed understanding of the physiological characteristics of newborns, in order to clear the cause of these iatrogenic diseases, the correct application of drugs. Many drugs through the liver and kidney metabolism, due to neonatal liver and kidney function has not yet