手足口病(HFMD)是婴幼儿常见的由肠道病毒引起的一种以口腔黏膜溃疡、皮肤疱疹和发热为主要临床表现的流行性传染疾病。多数患儿1周左右自愈,但少数会出现心肌炎、肺水肿、无菌性脑膜脑炎等并发症,若病情发展迅速可导致个别重症患儿死亡。目前手足口病缺乏特效药物,治疗以抗病毒、对症处理及预防严重并发症为主。本文就目前治疗手足口病常用中西药联合抗病毒的研究作一综述。 Hand, foot and mouth disease (HFMD) is a common infectious disease caused by enteroviruses in infants and young children, which is characterized by oral mucosal ulceration, skin herpes and fever as the main clinical manifestations. Most children recover about 1 week, but a few will have myocarditis, pulmonary edema, aseptic meningoencephalitis and other complications, if the rapid development of the disease can lead to individual deaths in critically ill children. Foot and mouth disease currently lack of special effects drugs, treatment with anti-virus, symptomatic treatment and prevention of serious complications. In this paper, the current treatment of hand, foot and mouth disease common Chinese and Western medicine combined antiviral research.