三十多年前,Pressman等就己提出用放射性核素(radionuclides)标记抗体作体内肿瘤定位的概念,并开创了这一领域的研究.但发展缓慢.只是近七年来,由于γ-闪烁照相术(gamma scintigraphy)的发展和一些抗肿瘤高纯度抗体的制备,才促进了这类研究的较快发展.特别是单克隆抗 More than thirty years ago, Pressman et al. proposed to use radionuclides as an in vivo tumor localization concept and initiated research in this area. However, the development has been slow. It was only in the past seven years because of γ-scintigraphy. The development of gamma scintigraphy and the preparation of some anti-tumor and high purity antibodies have promoted the rapid development of this type of research.