1.概要干扰素(IFN)是抗病毒蛋白质,在天然控制病毒感染中起重要作用。干扰素可分成α、β、ω、γ四种类型,它们在化学上相关,但抗原性各不相同。人干扰素由人体细胞本身在生命过程中产生,或在生长过程中经外界刺激,尤其是在病毒感染后产生。人α-干扰素共有22种亚型,这些亚型的166个(或165)氨基酸中有70%是相同的,但某些生物性质是不相同的。结构简单的β-干扰素和α-干扰素有许多相同的性质,共同有约30% 1. Summary Interferons (IFNs) are antiviral proteins that play an important role in the natural control of viral infections. Interferon can be divided into α, β, ω, γ four types, which are chemically related, but the antigenicity varies. Human interferons are produced by human cells themselves during life or by the outside world during growth, especially after infection with the virus. There are 22 subtypes of human interferon alpha, and 70% of the 166 (or 165) amino acids of these subtypes are identical, but some of the biological properties are not the same. The simple structure of interferon-beta and interferon alpha have many of the same properties, together about 30%