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例1 男,1岁6月。以发热,咳嗽4d入院。查体:T39C,咽充血,双侧扁桃体Ⅱ°肿大,无脓点,双肺闻及干罗音,心腹无异常。实验室检查WBC12.6×10~9/L,N0.22,L0.78。诊断为急性支气管炎。给静点生理盐水250ml加氨苄西林1.5g,病毒唑0.1g入壶1次/d。用药第3天正常输液过程中,入壶病毒唑2min后,发现颜面青紫,烦躁不不安,呼吸急促,口唇发绀,出冷汗,四肢发凉,心率168次/min,心音低钝。考虑病毒唑致过敏性休克。立即停止输液,吸氧,肌注地塞米松3mg,肾上腺素0.5mg,抢救0.5h后颜面转红,呼吸平稳,安静。继续静点氨苄西林3d,未再出现类似症状。
Example 1 Male, 1 year old in June. To fever, cough 4d admission. Physical examination: T39C, pharyngeal congestion, bilateral tonsil enlargement Ⅱ, no suppurative point, lung smell and dry rales, no abnormal heart. Laboratory tests WBC12.6 × 10 ~ 9 / L, N0.22, L0.78. Diagnosis of acute bronchitis. To static point saline 250ml ampicillin 1.5g, ribavirin 0.1g into the pot 1 / d. Medication on the 3rd day of normal infusion process, into the bottle of ribavirin 2min, found face bruising, irritability, shortness of breath, lips cyanosis, cold and sweat, cold limbs, heart rate 168 beats / min, low heart sound blunt. Consider ribavirin-induced anaphylactic shock. Immediately stop infusion, oxygen, intramuscular dexamethasone 3mg, epinephrine 0.5mg, face 0.5h rescue turn red, stable and quiet breathing. Continue to point ampicillin 3d, no recurrence of similar symptoms.