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二个或多个药物合并用药往往有其优点,可降低药物剂量和毒性,减少靶细胞和靶器官产生耐受性的机会以及提供药物协同作用的可能性。在估测药物合并用药的有效作用中,中心问题之一是缺乏如何用简单、合理而无需多次测量就能定量分析实验结果的公认方法。两
The combination of two or more drugs often has the advantage of reducing the dosage and toxicity of the drug, reducing the chances of tolerance of the target cells and target organs, and providing the possibility of synergistic effects of the drug. One of the central issues in estimating the effective role of drug combinations is the lack of a well-established method of using quantitatively analytical results in a simple and reasonable manner without the need for multiple measurements. Two