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目的:探讨α-1b干扰素宫颈局部注射联合复方莪术油栓剂治疗宫颈糜烂的疗效。方法:232例患者随机分为干扰素组(79例)莪术油组(75例)和联合治疗组(78例)。干扰素组采用重组人干扰素α-1b注射液宫颈局部注射治疗,莪术油组采用阴道置入复方莪术油栓剂治疗,联合治疗组采用以上二药同时治疗,评价疗效。结果:联合治疗组痊愈率明显高于干扰素组和莪术油组,相比较有统计学差异(P<0.05);联合治疗组Ⅲ度糜烂患者平均治愈时间为(8.4±0.6)周,明显高于中轻度(P<0.05)。结论:α-1b干扰素宫颈局部注射联合复方莪术油栓剂治疗宫颈糜烂方便无痛苦,效果显著,特别适合轻重度患者,是治疗宫颈糜烂的一种良好方法,值得推广使用。
Objective: To investigate the curative effect of local injection of α-1b interferon cervical injection combined with Ezhu oil suppository on cervical erosion. Methods: 232 patients were randomly divided into interferon group (79 cases) Curcuma oil group (75 cases) and combination therapy group (78 cases). Interferon group using recombinant human interferon alpha-1b injection of cervical local injection treatment, Curcuma oil group was treated with compound Ezhu oil suppository, the combined treatment group with the above two drugs simultaneously to evaluate the efficacy. Results: The cure rate of combination therapy group was significantly higher than that of interferon group and zedoary turmeric oil group (P <0.05). The average healing time of Ⅲ degree erosion group in combined therapy group was (8.4 ± 0.6) weeks, which was significantly higher In mild (P <0.05). Conclusion: Cervical injection of α-1b interferon combined with zedoary turmeric oil suppository in the treatment of cervical erosion is convenient and painless with obvious effect. It is especially suitable for patients with severe and severe cervical erosion. It is a good method to treat cervical erosion and is worth popularizing.