Dactylospongia属海绵中已报道的次生代谢产物主要包括倍半萜醌和倍半萜氢醌类、倍半萜衍生物、大环内酯及甾醇等结构类型,大多具有良好的生物活性,包括抗肿瘤、抗炎及抗菌等。本文根据化合物的结构类型综述了1989-2014年之间经文献报道的Dactylospongia属海绵的化学成分和生物活性,为该属海绵的进一步研究开发提供了参考。 The secondary metabolites reported in the sponges of Dactylospongia mainly include structural types such as sesquiterpene and sesquiterpene hydroquinones, sesquiterpene derivatives, macrolides and sterols, most of which have good biological activity, Tumor, anti-inflammatory and anti-bacterial. In this paper, the chemical composition and biological activity of Dactylospongia spongy sponge reported in the literature from 1989 to 2014 are reviewed according to the structure types of the compounds, which provides a reference for the further research and development of this sponge.