近年来,恶性肿瘤的治疗已取得了前所未有的进步,内科治疗已经渗透到肿瘤治疗的各个方面,并从最初的单纯姑息性治疗进入到了根治性治疗、或与手术及放疗有机地结合,以提高患者生存率、减少治疗损伤和改善患者生存质量的时代。1肿瘤内科治疗角色的转变在上个世纪50年代,化疗药物 In recent years, the treatment of malignant tumors has made unprecedented progress, medical treatment has penetrated into all aspects of cancer treatment, and from the initial simple palliative treatment into the radical treatment, or combined with surgery and radiotherapy to improve Patient survival, reduce the treatment of injury and improve the quality of life of patients with the era. 1 The role of oncology in the treatment of medical changes in the last century 50’s, chemotherapy drugs