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冠心病是现代社会严重危害人类健康,影响人们生活质量的一种心血管疾病。近年有研究发现,冠状动脉粥样硬化是一种脂质代谢紊乱性疾病[1],炎症反应诱使粥样硬化斑块不稳定,进而发生破裂,参与冠心病的发生发展过程[2]。脂蛋白相关磷脂酶A2(Lp-PLA2)是新近发现的一种与冠状动脉粥样硬化斑块相关的炎症标记物,可能与动脉粥样硬化(AS)的形成相关[3],并且是冠心病的一个独立的危险预测
Coronary heart disease is a cardiovascular disease that seriously endangers human health and affects people’s quality of life in modern society. In recent years, studies have found that coronary atherosclerosis is a disorder of lipid metabolism [1], inflammatory response induced atherosclerosis plaque instability, and then rupture, involved in the occurrence and development of coronary heart disease [2]. Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a newly discovered marker of inflammation associated with coronary atherosclerotic plaque, which may be related to the formation of atherosclerosis (AS) [3] An independent risk prediction for heart disease