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目的探讨肠内营养支持与肠外营养支持疗法在胃癌根治术后患者中的应用效果。方法选取2013年1月1日至2015年12月31日葫芦岛市连山区人民医院收治的胃癌并行胃癌根治术患者78例为研究对象,按随机数字表法分为肠内营养组和肠外营养组,每组39例。肠内营养组患者采取肠内营养支持,肠外营养组患者采取肠外营养支持,比较两组患者的临床效果。结果肠内营养组患者体重不变率及增加率均高于肠外营养组,肠内营养组营养吸收更佳,差异有统计学意义(P<0.05)。肠内营养组患者体重减轻率低于肠外营养组,肠外营养组营养吸收较差,差异有统计学意义(P<0.05)。肠内营养组患者术后血红蛋白、清蛋白、血清前蛋白水平均优于术前,且优于肠外营养组,差异均有统计学意义(均P<0.05)。肠内营养组患者住院时间及肛门排气时间均短于肠外营养组,差异均有统计学意义(均P<0.05)。肠内营养组患者并发症发生率低于肠外营养组,差异有统计学意义(P<0.05)。结论肠内营养支持疗法对胃癌根治术后的效果及安全性均较肠外营养支持更好,同时可以保护肠道黏膜,防止肠道细菌感染,减少并发症的发生,缩短肛门排气时间及住院时间。
Objective To investigate the effect of enteral nutrition support and parenteral nutrition support in patients with gastric cancer after radical operation. Methods From January 1, 2013 to December 31, 2015, 78 patients with radical resection of gastric cancer treated by gastric cancer in Lianshan People’s Hospital of Huludao City were enrolled and divided into enteral nutrition group and enteral parenteral nutrition group according to random number table Nutritional group, 39 cases in each group. Enteral nutrition group enteral nutrition support, parenteral nutrition group parenteral nutrition support, the clinical effect of two groups of patients were compared. Results The rate of invariability of body weight and increase rate of enteral nutrition group were higher than that of parenteral nutrition group. Enteral nutrition group had better nutrition absorption, the difference was statistically significant (P <0.05). The weight loss rate of enteral nutrition group was lower than that of parenteral nutrition group, while the parenteral nutrition group had poor nutrition absorption. The difference was statistically significant (P <0.05). The levels of hemoglobin, albumin and serum pre-albumin in enteral nutrition group were better than preoperative and better than those in parenteral nutrition group (all P <0.05). The length of hospital stay and anal exhaust in enteral nutrition group were shorter than those in parenteral nutrition group (all P <0.05). The incidence of complications in enteral nutrition group was lower than that in parenteral nutrition group, the difference was statistically significant (P <0.05). Conclusions Enteral nutrition supportive therapy is more effective and effective than parenteral nutrition in the treatment of gastric cancer after radical operation. At the same time, it can protect intestinal mucosa, prevent intestinal bacterial infection, reduce the incidence of complications, shorten the time of anal exhaust, and Hospitalization time.