[目的]探讨喉癌发病的危险因素,以便制订相应的预防对策和措施。[方法]采用以医院和社区为基础的1︰2配比病例对照研究,对110例经病理学确诊的喉癌患者及220例对照的相关资料进行条件Logistic回归分析。[结果]有声嘶史、吸烟、饮酒、职业暴露、有癌症家族史是喉癌的危险因素,其OR值依次为5.530,4.128,4.062,26.000,14.156;摄食蔬菜是保护因素,OR值为0.182。[结论]为了降低喉癌的发病率,应多食蔬菜,戒烟限酒,减少职业暴露。 [Objective] To explore the risk factors of laryngeal cancer in order to formulate corresponding preventive measures and measures. [Methods] Based on a 1: 2 matched case-control study based on hospital and community, conditional logistic regression analysis was performed on 110 pathologically-confirmed laryngeal cancer patients and 220 controls. [Results] The incidence of cries of hoarseness, smoking, drinking, occupational exposure, and family history of cancer were risk factors for laryngeal cancer. The OR values ​​were 5.530, 4.128, 4.062, 26.000 and 14.156, respectively. . [Conclusion] In order to reduce the incidence of laryngeal cancer, should eat more vegetables, quit smoking limit alcohol, reduce occupational exposure.