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目的探讨血清缺血修饰白蛋白和肌酸激酶同工酶联合检测在急性冠脉综合征(ACS)早期诊断中的价值。方法测定82例ACS患者和80例健康对照者血清IMA及CK-MB浓度。结果联合IMA和CK-MB诊断ACS,敏感度提高至92.9%,此时特异度为67.0%,联合诊断的PPV和NPV分别为76.4%,89.0%。结论联合检测IMA和CK-MB可提高联合诊断敏感度,提高ACS的诊断效能。
Objective To investigate the value of combined detection of serum ischemic-modified albumin and creatine kinase isoenzyme in the early diagnosis of acute coronary syndrome (ACS). Methods Serum IMA and CK-MB concentrations were measured in 82 patients with ACS and 80 healthy controls. Results The diagnostic accuracy of IMA and CK-MB in diagnosis of ACS was 92.9% and the specificity was 67.0%. The combined diagnosis of PPV and NPV was 76.4% and 89.0% respectively. Conclusions Combined detection of IMA and CK-MB can improve the diagnostic sensitivity and improve the diagnostic efficiency of ACS.