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用比较力场分析研究了 3 ,4 二甲基 4 ( 3 羟基苯基 )哌啶及其衍生物类吗啡拮抗物的结构与抑食活性的关系 ,考察了网格结构和探针原子的影响 .结果表明 ,立体效应和静电作用场是描述其抑食活性和进行结构性能关系研究的最重要的结构参数
The comparative analysis of the structure and antifeedant activity of morphine antagonists of 3,4-dimethyl-4 (3-hydroxyphenyl) piperidine and its derivatives with 3,4-dimethyl-4-hydroxyphenylpiperidine The results show that the stereoscopic effect and the electrostatic field are the most important structural parameters describing the relationship between their suppression activity and the structural properties