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采用ＮＡＤＰＨ二磷酸酶组织化学方法，研究先天性巨结肠症ＮＡＮＣ抑制性神经系统。结果提示狭窄段肠管缺乏ＮＯＳ阳性神经丛，肌层内有散在神经纤维，有时可见到粗纤维或小神经干；正常结肠和巨结肠正常段富含阳性神经节细胞和神经纤维。提示ＮＯ与先天性巨结肠发病机理有关。
Using NADPH bisphosphatase histochemistry to study the NANC inhibitory nervous system of Hirschsprung’s disease. The results suggest that the narrow segment of the intestine is deficient in NOS-positive plexus, scattered nerve fibers in the muscle layer, and sometimes can be seen in the coarse fibers or small nerve trunk; normal colon and megacolon normal segment is rich in positive ganglion cells and nerve fibers. Tip NO and pathogenesis of Hirschsprung’s disease.