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以大鼠递增负荷力竭性运动为模型，利用低温电子自旋共振（ＥＳＲ）技术，分别测定安静时、运动过程中、运动后即刻、运动后恢复期３０ｍｉｎ、２ｈ、４ｈ及８ｈ脑组织的氧自由基（ＯＴＲ）信号强度，同时测定ＳＯＤ活力和ＭＤＡ含量。结果显示：脑组织在运动过程中ＯＦＲ信号强度逐渐增加，并具有运动强度依赖的阶段性，恢复期４小时达到高峰；ＳＯＤ活性运动时无明显改变，恢复期２ｈ升至峰值；脂质过氧化水平（ＭＤＡ）在整个运动过程中及恢复期无显著变化。提示该运动模型所引起的脂质过氧化尚未累及中枢神经系统，并且脑组织可能存在重要而有效的抗氧化体系。
The rat model of incremental exhaustive exercise was established. The ESR techniques were used to measure the changes of brain tissue at rest, during exercise, immediately after exercise, and after 30 minutes, 2 hours, 4 hours and 8 hours of convalescent exercise Oxygen free radical (OTR) signal intensity, SOD activity and MDA content were measured simultaneously. The results showed that the OFR signal intensity gradually increased in brain during exercise, and had intensity-dependent stage. The recovery peak reached peak at 4 hours. SOD activity did not change during exercise and peaked at 2 h recovery time. Lipid peroxidation There was no significant change in the level of MDA during the whole exercise and recovery period. It is suggested that the model of lipid peroxidation caused by this model has not involved the central nervous system, and there may be an important and effective antioxidant system in brain tissue.