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目的 探讨胃肠道恶性间质瘤的临床诊断与治疗。方法 回顾性分析 1993~ 1999年 2 2例胃肠道恶性间质瘤病人的临床资料。结果 胃部肿瘤 14例 ,小肠肿瘤 8例。其中 5例高度恶性 ,17例低度恶性。 1例广泛转移行肝结节活检 ,术后 4个月死亡。 4例行姑息切除 ,1例复发。其余行根治术 ,无病生存最长达 5年。结论 要提高对胃肠道恶性间质瘤的认识 ,加强免疫组化检查 ,确定良恶性及恶性程度 ,根治性手术对预后及防止复发有一定意义。
Objective To investigate the clinical diagnosis and treatment of gastrointestinal malignant stromal tumors. Methods The clinical data of 22 patients with gastrointestinal malignant stromal tumors from 1993 to 1999 were retrospectively analyzed. Results of gastric cancer in 14 cases, 8 cases of small bowel cancer. Five of them were highly malignant and 17 were low-grade. A case of extensive metastatic hepatic nodules biopsy, 4 months after the death. 4 cases of palliative resection, 1 case of recurrence. The remaining line radical surgery, disease-free survival of up to 5 years. Conclusion To improve the awareness of gastrointestinal malignant stromal tumors, strengthen immunohistochemical examination to determine the degree of benign and malignant, radical surgery for prognosis and prevent recurrence of some significance.