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目的分析青年妇女宫颈浸润癌的临床特点及预后。方法对1976年7月~1992年7月采用放疗、化疗、手术及冷冻两种以上方法综合治疗的77例青年妇女宫颈浸润癌进行回顾性分析。结果77例患者占同期宫颈癌的3.88%,平均年龄31.9岁。肿瘤直径大于4cm者47例;腺癌29例,占37.66%;组织学分化为Ⅲ级32例,其中腺癌11例,鳞癌21例。ⅡB期以上为58例,占75.32%。5年生存率为50.65%。血行转移以腺癌多见,多发生在半年之内,死亡率高。结论青年妇女宫颈癌影响预后的主要因素为临床分期、组织学类型、组织学分化程度及原发肿瘤的大小。
Objective To analyze the clinical features and prognosis of cervical cancer in young women. Methods From July 1976 to July 1992, 77 young women with cervical cancer who underwent combined treatment with radiotherapy, chemotherapy, surgery and cryotherapy were retrospectively analyzed. Results 77 patients accounted for 3.88% of cervical cancer over the same period, with an average age of 31.9 years. Tumor diameter more than 4cm in 47 cases; adenocarcinoma in 29 cases, accounting for 37.66%; histological differentiation of grade 32 in 32 cases, including adenocarcinoma in 11 cases, squamous cell carcinoma in 21 cases. 58 cases were in stage IIB, accounting for 75.32%. 5-year survival rate was 50.65%. Blood metastasis to more common in adenocarcinoma, occurred in more than six months, the high mortality rate. Conclusion The main factors affecting the prognosis of cervical cancer in young women are clinical stage, histological type, histological differentiation degree and the size of primary tumor.