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目的探讨肺炎支原体消化系统损害及其相关因素。方法选择43例肺炎支原体感染并发消化系统损害患者,分析患者的临床特征及并发消化系统损害的相关因素。结果合并肺外消化系统损害患者的TNF-α水平明显高于单纯肺炎支原体感染患者(P<0.05);发热、热程、抗感染起始时间3个项目在伴肺外消化系统损害组与无肺外消化系统损害组之间的例数差异明显(P<0.05);Logistic回归方程显示发热、热程、抗感染起始时间是伴肺外消化系统损害的独立危险因素。结论肺炎支原体感染合并肺外消化系统损伤的发生率较高,持续发热可能是引起肺外消化系统损伤的相关因素之一,早期应用大环内酯类抗生素可减少肺外消化系统损伤的发生。
Objective To investigate the damage of digestive system of Mycoplasma pneumoniae and its related factors. Methods Forty-three patients with mycoplasma pneumoniae infection and digestive system damage were selected. The clinical characteristics and the related factors of digestive system damage were analyzed. Results The levels of TNF-α in patients with combined pulmonary digestive system damage were significantly higher than those in patients with pure Mycoplasma pneumoniae infection (P <0.05). The three items of fever, heat stroke and anti-infective onset time were significantly higher in patients with and without pulmonary digestive system damage There were significant differences in the number of patients with extrapulmonary digestive system damage (P <0.05). Logistic regression equation showed that fever, heat stroke and anti-infective onset time were independent risk factors of pulmonary extraintestinal digestive system damage. Conclusions The incidence of Mycoplasma pneumoniae infection combined with extrapulmonary digestive system injury is high. Continuous fever may be one of the related factors that cause pulmonary digestive system damage. Early use of macrolide antibiotics can reduce the incidence of extra-pulmonary digestive system damage.