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通过回顾性研究，分析成人原发性肾病综合征１７９例的病理类型、激素疗效及可能并发症。结果表明：①病理改变以系膜增生性肾炎、肾小球微小病变病多见，膜性肾病和局灶节段性肾小球硬化症其次；②病理改变是预测疗效的可靠依据。常规激素治疗８周，肾小球微小病变病的疗效最好，而７例膜增生性肾炎的效果较差；③病理改变是指导治疗的主要方法。适当延长激素的疗程，可进一步提高肾小球微小病变病、膜性肾病及局灶节段性肾小球硬化症的疗效；④疗程中可能出现某些并发症，其中尤以老年人多发。
Through retrospective study, 179 cases of adult primary nephrotic syndrome pathological type, hormone efficacy and possible complications were analyzed. The results showed that: ① pathological changes to mesangial proliferative glomerulonephritis, glomerular paroxysmal disease more common, membranous nephropathy and focal segmental glomerulosclerosis followed; ② pathological changes are reliable predictors of efficacy. Conventional hormone therapy for 8 weeks, the best effect of minimal disease glomerular, and 7 cases of membranoproliferative glomerulonephritis less effective; ③ pathological changes are the main method of guiding treatment. Appropriate to extend the course of hormones, can further improve the glomerular minor disease, membranous nephropathy and focal segmental glomerulosclerosis effect; ④ course of treatment may occur in some complications, especially in the elderly multiple.