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目的研究甲型HlNl流行性感冒(流感)的临床表现及实验室检查结果,总结其特点。方法回顾性分析93例确诊甲型HlNl流感患者临床表现、实验室和影像学检查及治疗情况。结果 93例患者高发年龄为18～64岁;多发症状为发热87例(93.5%)、咳嗽85例(91.4%)和咽痛61例(65.6%);常见阳性体征为咽部充血86例(92.5%)和扁桃体肿大20例(21.5%)。白细胞计数为(5.27±0.76)×109/L,中性粒细胞为(2.17±0.25)×109/L,淋巴细胞为(5.52±0.73)×109/L,C反应蛋白为(11.73±2.09)mg/L。胸部X线检查发现35例(43.2%)表现为局部或广泛肺纹理增粗、紊乱或支气管炎,6例(7.4%)表现为肺内斑片状实变影。机械通气支持治疗13例,死亡4例。结论中国目前确诊的甲型H1N1流感病例以非输入性病例为主;其性别及年龄构成与国外相似,其流行病学和临床表现与普通季节性流感类似。重症及危重甲型H1NI流感病例应该早期治疗。
Objective To study the clinical manifestations and laboratory findings of Influenza A (H1N1) influenza and to summarize its characteristics. Methods Retrospective analysis of 93 cases of confirmed influenza A (H1N1) influenza clinical manifestations, laboratory and imaging studies and treatment. Results Ninety-three patients had a high incidence of 18-64 years old. The most common symptoms were fever in 87 cases (93.5%), cough in 85 cases (91.4%) and sore throat in 61 cases (65.6% 92.5%) and tonsil enlargement in 20 cases (21.5%). The number of leukocytes was (5.27 ± 0.76) × 109 / L, the number of neutrophils was (2.17 ± 0.25) × 109 / L, the number of lymphocytes was (5.52 ± 0.73) × 109 / L and the level of C - reactive protein was (11.73 ± 2.09) mg / L. Chest X-ray examination found 35 cases (43.2%) showed local or extensive thickening of the lungs, or bronchitis, and 6 cases (7.4%) showed patchy consolidation of the lungs. Mechanical ventilation support treatment in 13 cases, 4 patients died. Conclusions The cases of Influenza A (H1N1) in China are mainly non-infrequent cases. Their gender and age are similar to those of other countries. Their epidemiological and clinical manifestations are similar to that of seasonal flu. Severe and critically ill cases of type A H1N1 influenza should be treated early.